In Reference to the following:

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As a beginner, it may be easier for you to use the "Bottom Up" approach and design each part of the bike as separate parts files and them create an assembly where you insert and align each component as required. I say this because the bike likely will already be designed (unless you plan on designing a unique bike as you go).
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During the "Bottom Up" approach, and as you create each individually modeled part, orient each part in relation to the world WCS such that the mounting face of the part is positioned and centered on the world XY plane. I've found that this makes it easier to place assembly constraints when components are instanced (nserted) into the assembly.

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