Source:
VX Technical Support, VX CAD/CAM
Try to settle on a tolerance value that is right for the size and complexity of the part before you begin a design. A tolerance value that is too small will cause increased processing times and increase the complexity and size of the model's database. A value that is too large may cause the system to ignore features that are very small relative to larger features and decrease the accuracy of intersections and curve/face approximations.
The right tolerance value is one that is only small enough to allow the accurate definition of the smallest anticipated feature and the amount of geometric variation that can be tolerated.
See also:
Use caution when editing geometry tolerances