Join our CAD community forums where over 25,000 users interact to solve day to day problems and share ideas. We encourage you to visit, invite you to participate and look forward to your input and opinions. Acrobat 3D, AutoCAD, Catia, Inventor, IronCAD, Creo, Pro/ENGINEER, Solid Edge, SolidWorks, and others.
You can delete any setups that are currently being used from page setup manager. Just right click on the one you want to delete and choose delete. If you're wanting to get rid of one being used you'll have to change the page setup for the layout it is being used on or delete that layout tab.